Wednesday, March 27th 08:00-18:00, Exhibition Session Code A7.a

DEEP PHENOTYPING OF THE 5XFAD MOUSE MODEL USING THE MODEL-AD PIPELINE
A. Oblak, H. Williams, G. Carter, S. Sukoff-Rizzo, M. Sasner, P. Territo, G. Howell, B. Lamb.
Indiana University School of Medicine, Stark Neurosciences Research Institute, Indianapolis, USA.
The Jackson Laboratory, MODEL-AD, Bar Harbor, USA.
Indiana University School of Medicine, Radiology & Imaging Sciences, Indianapolis, USA.

MODELS OF LATE ONSET ALZHEIMER’S DISEASE: THE MODEL-AD CONSORTIUM
A. Oblak, G. Carter, G. Howell, S. Sukoff-Rizzo, M. Sasner, P. Territo, H. Williams, B. Lamb, A. Mortazavi, M. Wood, S. Forner, G. MacGregor, A. Tenner, K. Green, F. LaFerla.
Indiana University School of Medicine, Stark Neurosciences Research institute, Indianapolis, USA.
The Jackson Laboratory, MODEL-AD, Bar Harbor, USA.
University of California Irvine, MODEL-AD, Irvine, USA.

TREM2R47H MICE SHOW A TWO-FOLD REDUCTION IN EXPRESSION AND PROTEIN LEVELS OF TREM2
A. Oblak, R. Pandey, G. Carter, H. Williams, G. Howell, M. Sasner, B. Lamb.
Indiana University School of Medicine, Stark Neurosciences Research Institute, Indianapolis, USA.
The Jackson Laboratory, MODEL-AD, Bar Harbor, USA.

EVALUATION OF CHRONIC TREATMENT WITH LEVETIRACETAM ON PHARMACOKINETCS AND PHARMACODYNAMICS IN 5XFAD MICE
S. Rizzo, S. Quinney, K. Onos, K. Keezer, L. Haynes, D. Jones, A. Masters, C. Biesdorf De Almeida, J. Meyer, J. Peters, S. Persohn, A. Bedwell, D. McKinzie, M. Sasner, G. Howell, H. Williams, A. Oblak, B. Lamb, P. Territo.
The Jackson Laboratory, Center for Biometric Analysis, Bar Harbor, USA.
Indiana University, School of Medicine, Indianapolis, USA.
The Jackson Laboratory, Institute for Mammalian Genomics, Bar Harbor, USA.

NOVEL MOUSE MODELS OF LATE-ONSET ALZHEIMER’S DISEASE EXPRESSING RISK VARIANTS AT GWAS LOCI
M. Sasner, A. Oblak, H. Williams, C. Preuss, G. Carter, G. Howell, B. Lamb.
The Jackson Laboratory, MODEL-AD, Bar Harbor, USA.
Indiana University, Stark Neurosciences Research Institute, Indianapolis, USA.

CHARACTERIZATION OF A NOVEL MOUSE MODEL EXPRESSING APOE4 AND TREM2*R47h FOR FURTHERING THE UNDERSTANDING OF LATE ONSET ALZHEIMER’S DISEASE
M. Sasner, A. Oblak, H. Williams, S. Rizzo, P. Territo, G. Howell, B. Lamb.
The Jackson Laboratory, MODEL-AD, Bar Harbor, USA.
Indiana University, Stark Neurosciences Research Institute, Indianapolis, USA.

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