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MODEL-AD presentations at AAIC

We will be presenting our progress at the Alzheimer’s Association International Conference in London in July.

Monday July 17

Genetic Factors of Alzhemer’s Disease:

Cross Study Integrative Network Analysis Identification of AD Disease Etiology 



Wednesday July 19

Basic and Translational Science: Development of New Models and Analysis Methods:

Model Organism Development and Evaluation for Late-Onset Alzheimer’s Disease: MODEL-AD



Wednesday July 19

Developing Topics:

Creating a Humanized Mouse Model of CR1 and CR2 to Better Model Alzheimer’s Disease Risk Factors



Wednesday July 19

Developing Topics:

Novel Candidate Loci for Late-Onset Alzheimer’s Disease from Bayesian Mixed Modeling of Whole-Genome and Whole-Exome Sequencing


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MODEL-AD Mini-Symposium 5/22/17

The Jackson Laboratory hosted a MODEL-AD Mini-Symposium on Monday, May 22, 2017 from 2:15 to 5:15 p.m in the LCC Auditorium at our Bar Harbor, Maine campus. The symposium included updates from Alzheimer’s Disease experts and was followed by a poster session. For more information, please contact Mike Sasner (mike.sasner@jax.org).


  • 2:15 pm: Welcome – Gareth Howell, Ph.D., Associate Professor, The Jackson Laboratory
  • 2:30 pm: “Unraveling the Role of TREM2 in Alzheimer’s Disease Pathogenesis” Bruce Lamb, Ph.D., Roberts Family Chair in Alzheimer’s Disease Research, Executive Director, Stark Neurosciences Research Institute, Indiana University School of Medicine
  • 2:45 pm: “Research at the Toronto Dementia Research Alliance” – Barry Greenberg, Ph.D., Director of Strategy, Toronto Dementia Research Alliance, University Health Network, Toronto
  • 3:00 pm: “Preclinical Development of a CNS-active, Isoform-selective, p38alpha MAPK Inhibitor for Alzheimer’s Disease” – Linda Van Eldik, Ph.D., Director, Alzheimer’s Disease Center, University of Kentucky, Co-Director, Kentucky Neuroscience Institute, Vernon Smith Endowed Chair in Alzheimer’s Research
  • 3:15 pm: “Systems Genetics Analysis of Resilience to Alzheimer’s Disease”  Catherine Kaczorowski, Ph.D., Assistant Professor, The Jackson Laboratory
  • 3:30 pm: “Appropriate Use of Animal Models to Translate Aβ Lowering Effects of BACE1 Inhibition to the Clinic” – Dave McKinzie, Ph.D., Research Fellow & Head of In Vivo Pharmacology, Eli Lilly
  • 3:45 pm: “MODEL-AD: Creating the Next Generation of Animal Models for Alzheimer’s Disease” – Greg Carter, Ph.D., Associate Professor, The Jackson Laboratory
  • 4:00 pm: Collaborative Frameworks and Open Science: New Frontiers in Systems Biology” – Ben Logsdon, Ph.D., Senior Scientist, Sage Bionetworks
  • 4:15 pm: Poster session with wine and cheese
  • 5:15 pm: Adjourn