The Disease Modeling Project aims to create 8 new mouse models relevant to the study of late-onset AD per year.  All of these will be made available for both academic and for-profit use from the Jackson Lab AD Mouse Model Resource.

At least 6 of these will be phenotyped at 12 months of age.  Those models exhibiting AD-like properties will be fully characterized at 2,6,12 and 18 months of age, with the best models then being passed to the Preclinical Testing Core.

DMP Flow Chart v2