Common nameGenetic backgroundStrain NomenclatureAvailability JAX #Source
Familial AD models     
5XFADB6JB6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjaxlive8730Bob Vassar
APP/PS1B6JB6.Cg-Tg(APPswe,PSEN1dE9)85Dbo/Mmjaxlive5864Dave Borchelt
3XTg-ADmixed B6; 129B6;129-Tg(APPSwe,tauP301L)1Lfa Psen1tm1Mpm/Mmjaxlive4807Frank LaFerla
3XTg-ADB6JB6.Cg-Tg(APPSwe,tauP301L)1Lfa Psen1tm1Mpm/Jlive8880Frank LaFerla
3xTg-AD129129S4.Cg-Tg(APPSwe,tauP301L)1Lfa Psen1tm1Mpm/LfaJcryo31988MODEL-AD
hTauB6JB6.Cg-Mapttm1(EGFP)KltTg(MAPT)8cPdav/Jlive5491Peter Davies
Late-onset AD-related models    
APOE models     
APOE4/Trem2*R47HB6JB6.Cg-Apoetm1.1(APOE*4)AdiujTrem2em1Adiuj/Jlive28709MODEL-AD
APOE4 KIB6JB6.Cg-Apoetm1.1(APOE*4)Adiuj/Jlive27894MODEL-AD
APOE3 KIB6JB6.Cg-Apoeem2(APOE*)Adiuj/Jlive29018MODEL-AD
APOE2 KIB6JB6.Cg-Apoeem3(APOE*)Adiuj/Jtbd29017MODEL-AD
APP models     
hAbeta-loxP-KImixed B6J; B6NB6(SJL)-Apptm1.1Aduci/Jlive30898MODEL-AD
hAbeta-loxP-KIB6NJB6N(Cg)-Apptm1.1Aduci/Jtbd32013MODEL-AD
hAbeta KIB6J-APOE4/Trem2*R47HB6.Cg-Apoetm1.1(APOE*4)AdiujAppem#1Adiuj Trem2em1Adiuj/Jlive30670MODEL-AD
App KOB6J-APOE4/Trem2*R47HB6.Cg-Apoetm1.1(APOE*4)AdiujAppem2Adiuj Trem2em1Adiuj/Jcryo31722MODEL-AD
Trem2 models     
Trem2*R47HB6JC57BL/6J-Trem2em1Adiuj/Jlive27918MODEL-AD
Trem2*Y38CB6JC57BL/6J-Trem2em3Adiuj/Jcryo29725MODEL-AD
Trem2 KOB6JC57BL/6J-Trem2em2Adiuj/Jlive27197MODEL-AD
floxed Trem2B6JB6(C3)-Trem2tm1c(EUCOMM)Wtsi/AdiujJlive29853MODEL-AD
AD GWAS LOAD variant models    
Abca7*A1527G SNPB6J-APOE4/Trem2*R47HB6.Cg-Apoetm1.1(APOE*4)AdiujAbca7em#2Adiuj  Trem2em1Adiuj/Jlive30283MODEL-AD
Abca7 KOB6J-APOE4/Trem2*R47HB6.Cg-Apoetm1.1(APOE*4)AdiujAbca7em#1Adiuj Trem2em1Adiuj/Jlive30320MODEL-AD
Ceacam1 KOB6J-APOE4/Trem2*R47HB6.Cg-Apoetm1.1(APOE*4)AdiujCeacam1em#1Adiuj  Trem2em1Adiuj/Jlive30673MODEL-AD
Clasp2 L163P SNPB6J-APOE4/Trem2*R47HB6.Cg-Apoetm1.1(APOE*4)Adiuj Clasp2em1Adiuj Trem2em1Adiuj/J~Oct ’1931944MODEL-AD
hCR1 KIB6JB6(Cg)-Cr2tm1.1(CR2,CR1)How/HowJcryo27713MODEL-AD
hCR1 KIB6J-APOE4/Trem2*R47HB6.Cg-Cr2tm1(CR2,CR1)How Apoetm1.1(APOE*4)Adiuj Trem2em1Adiuj/Jtbd31668MODEL-AD
Il1rap exon 2 KOB6J-APOE4/Trem2*R47HB6.Cg-Apoetm1.1(APOE*4)AdiujIl1rapem#1Adiuj  Trem2em1Adiuj/Jlive30304MODEL-AD
Kif21b T82T SNPB6J-APOE4/Trem2*R47HB6.Cg-Kif21bem1Adiuj Apoetm1.1(APOE*4)Adiuj Trem2em1Adiuj/Jcryo31938MODEL-AD
Meox2 KO (HET)B6J-APOE4/Trem2*R47HB6(Cg)-Apoetm1.1(APOE*4)Adiuj Meox2tm1(cre)Sor Trem2em1Adiuj/Jtbd33770Soriano/MODEL-AD
Mthfr*C677T SNPB6J-APOE4/Trem2*R47HB6.Cg-Mthfrem1Adiuj Apoetm1.1(APOE*4)Adiuj Trem2em1Adiuj/Jcryo30922MODEL-AD
Mtmr4*V297G SNPB6J-APOE4/Trem2*R47HB6(SJL)-Apoetm1.1(APOE*4)Adiuj Mtmr4em1Adiuj Trem2em1Adiuj/Jtbd31950MODEL-AD
Plcg2*M28L SNPB6J-APOE4/Trem2*R47HB6.Cg-Apoetm1.1(APOE*4)AdiujPlcg2em2Adiuj Trem2em1Adiuj/Jlive30674MODEL-AD
Plcg2*P522RB6J-APOE4/Trem2*R47HB6.Cg-Apoetm1.1(APOE*4)AdiujPlcg2em1Msasn Trem2em1Adiuj/Jcryo30771JAX
Plcg2 KOB6JB6.Cg-Plcg2em2Adiuj/Jcryo29910MODEL-AD
Shc2*V433M SNPB6J-APOE4/Trem2*R47HB6(SJL)-Apoetm1.1(APOE*4)Adiuj Shc2em1Adiuj Trem2em1Adiuj/Jtbd31952MODEL-AD
Slc6a17*P61P SNPB6J-APOE4/Trem2*R47HB6(SJL)-Slc6a17em1Adiuj Apoetm1.1(APOE*4)Adiuj Trem2em1Adiuj/Jtbd31948MODEL-AD
Snx1 D465N SNPB6J-APOE4/Trem2*R47HB6.Cg-Apoetm1.1(APOE*4)Adiuj Snx1em1Adiuj Trem2em1Adiuj/Jcryo31942MODEL-AD
Sorl1 A528T SNPB6J-APOE4/Trem2*R47HB6.Cg-Apoetm1.1(APOE*4)Adiuj Sorl1em1Adiuj Trem2em1Adiuj/Jcryo31940MODEL-AD